Thyroid hormones are critical regulators of metabolism, growth, and development. The primary hormones produced by the thyroid gland are thyroxine (T4) and triiodothyronine (T3). These hormones influence nearly every cell and organ in the body, ensuring that they function correctly and efficiently.
Hypothyroidism is a medical condition where the thyroid gland, fails to produce sufficient amounts of thyroid hormones. These hormones are crucial for regulating metabolism, so when they're low, it can slow down many of the body's functions. Common symptoms include fatigue, weight gain, sensitivity to cold, constipation, dry skin, and hair loss.
Causes
* Autoimmune Disease: The most common cause is Hashimoto’s thyroiditis, where the immune system attacks the thyroid gland.
* Thyroid Surgery: Removal of the thyroid gland or part of it can lead to hypothyroidism.
* Radiation Therapy: Treatment for cancers of the head and neck can damage the thyroid gland.
* Medications: Certain drugs can affect thyroid function, such as lithium.
* Iodine Deficiency: Iodine is crucial for thyroid hormone production. In areas where iodine is deficient in the diet, hypothyroidism is more common.
Signs and Symptoms
* Tiredness.
* More sensitivity to cold.
* Constipation.
* Dry skin.
* Weight gain.
* Puffy face.
* Hoarse voice.
* Coarse hair and skin.
* Muscle weakness.
* Muscle aches, tenderness and stiffness.
* Menstrual cycles that are heavier than usual or irregular.
* Thinning hair.
* Slowed heart rate, also called bradycardia.
* Depression.
* Memory problems.
Risk Factors
* Women: Women are significantly more likely than men to develop hypothyroidism. Hormonal changes and autoimmune factors are thought to contribute to this increased risk.
* Genetics: A family history of thyroid disease, including hypothyroidism or other thyroid disorders, increases your likelihood of developing the condition.
* Type 1 Diabetes: This autoimmune disorder can be associated with other autoimmune conditions, including Hashimoto’s thyroiditis.
* Celiac Disease: Individuals with celiac disease, an autoimmune condition triggered by gluten, are at a higher risk of developing thyroid disorders.
* Hyperthyroidism Treatment: Treatments for hyperthyroidism, such as radioactive iodine or anti-thyroid medications,
* Radiation to Neck or Chest: Radiation treatment for cancers in the neck or upper chest can damage the thyroid gland and lead to hypothyroidism.
* Surgical Procedures: Surgery to remove part or all of the thyroid gland can reduce the gland’s ability to produce hormones, leading to hypothyroidism.